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About Cardiometabolic Diseases (CMD)

What are CMDs?

Cardiometabolic diseases refer to a cluster of closely linked health conditions that together greatly increase the likelihood of developing heart disease, stroke, and type 2 diabetes. These conditions include high blood pressure, elevated blood sugar, unhealthy cholesterol or triglyceride levels, and excess body fat, especially around the waist. When they occur together, they not only worsen overall health but also accelerate damage to the heart, blood vessels, and other vital organs.

Global Statistics

  • Around 18–20 million deaths annually worldwide from cardiovascular diseases, the leading cause of death globally.
  • Over 500 million people worldwide live with cardiovascular disease.
  • Cardiovascular disease remains the top cause of mortality worldwide.
  • A majority of cases are preventable through lifestyle and risk factor management (e.g., diet, exercise, blood pressure, tobacco, cholesterol, diabetes control).

U.S. Statistics

  • More than half of U.S. adults have multiple chronic conditions (≥2).
  • In 2023, 76.4% (representing 194 million) of US adults reported 1 or more chronic conditions.
  • In 2020–2021, cardiovascular disease (CVD) cost the U.S. about $417.9 billion in combined direct and indirect costs.
  • Heart disease (and cardiovascular disease more broadly) is the leading cause of death in the U.S.